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Publications #5: Δεδομένα για το Άσθμα και τη ΧΑΠ

Πρόσφατες δημοσιεύσεις στο Αναπνευστικό, επιλεγμένες από την ομάδα της ιατρικής πληροφόρησης της Chiesi (Chiesi Global Medical Information Team).

15 λεπτά

Ultra processed foods (UPFs) increased mortality risk from chronic respiratory diseases (CRDs) in a large study of ~100,000 people in the United States.

Diets high in UPFs and dietary inflammatory index increased the risk of mortality from CRDs, including COPD and lung cancer. Healthy diets rich in antioxidants reduced the risk of death from CRD overall and COPD, which may be due to effects on inflammatory potential, although the impact of UPFs was not offset.

Women with asthma, including those who had asthma for a year or more before conception, face an increased risk of neonatal and pregnancy-related complications.

In a study of over 400,000 pregnancies in Canada, nearly 9% of women had asthma. The risks for preterm birth, low birth weight and caesarean section delivery were highest in women with active and current asthma, but were also elevated in women with a previous history of asthma. Risks increased with particular asthma phenotypes and lack of prenatal education.

Noise during nighttime has a disruptive effect on sleep quality in individuals with COPD and increases their risk of acute exacerbations.

A study involving 518 people in China with COPD found that exposure to high noise levels (≥40 dB) during nighttime sleep hours significantly increased the likelihood of escalated therapy and urgent hospitalization for COPD exacerbations. This was up to twice as high compared with people experiencing lower noise levels.

The largest study of e-cigarettes and health outcomes to date, the All of Us research program in over 249,000 individuals in the United States, has shone new light on the cardiometabolic consequences of exclusive use of e-cigarettes.

Exclusive use of e-cigarettes significantly increased the risk of COPD by over 2-fold compared with non-use. However, it was not associated with hypertension, type 2 diabetes, heart failure or atherosclerotic cardiovascular disease.

The prevalence of asthma is high in people with type 2 diabetes and is not explained just by BMI, which is an important risk factor for both conditions.

A study of over 25,000 adults in Sweden found a 47% higher prevalence of current asthma among individuals with type 2 diabetes, even after adjusting for BMI, as well as other demographic and socioeconomic factors. Brothers and sisters with asthma were at increased odds of type 2 diabetes, indicating shared familial genetic and environmental risk factors.

A Global Working Group of experts across 40 countries has developed a blueprint in a first comprehensive study for the identification and management of cardiopulmonary risk in patients with COPD.

The experts call for improved cardiopulmonary risk identification and stratification in COPD as well as clinical pathways and integrated models for identifying comorbid COPD and cardiovascular disease. There is also a call to action for novel therapies and defining optimal management strategies.

People with asthma who prefer mornings have better health-related quality of life.

A morning-type chronotype was associated with less fatigue and better emotional function than an evening type in an international study of 691 people with asthma. Less anxiety, less depression, reduced alcohol abuse and less sleep deprivation partially explained these relationships.

A study of ~4 million individuals in South Korea has given unique insights into the relationship between COPD-related factors and death by suicide.

Death by suicide was more common among people with COPD than people without COPD; smoking increased this risk. One novel finding of this study is that COPD increased the risk of suicide by 33% even in people who have never smoked. Another finding is that the risk of suicide was particularly high among those who have depression or anxiety. Despite this, less than 10% of people with COPD received treatment for these mental disorders.

Eating fast food 3 times a week or more increased emergency department visits for asthma in a large study of over 11,500 adults with asthma in California, United States.

Irrespective of BMI, an improved diet by reducing fast food consumption and increasing fruit and vegetable intake may be beneficial for adults with asthma and result in fewer emergency department visits due to asthma.

Airborne microplastics and nanoplastics originate from a variety of sources including roadside dust and domestic waste and can induce inflammation and oxidative stress when inhaled, ingested or on contact with skin.

Global distribution of these particulate plastics through the atmosphere poses significant health risks, especially when present in particulate matter and in urban areas, according to researchers from Taiwan. Mitigation strategies such as advanced oxidation processes and bioremediation alongside public health policies are needed to counter these adverse effects.

A novel AI model using dual-sound analysis shows strong potential to improve diagnostic practices in asthma and COPD management.

When differentiating between asthma and normal cases, the automated, lightweight model achieved 83% and 94% accuracy of cough and respiratory sounds, respectively. This international study suggests that advancements in AI-based detection of respiratory diseases may be beneficial to clinicians and respiratory healthcare professionals globally.

Despite improvements, COPD remains a significant health issue internationally, with older adults, men and people exposed to tobacco and pollution predicted to be particularly affected by 2050.

Based on data from the Global Burden of Disease 2021 study, analysis of the COPD burden in the Original BRICS countries between 1990 and 2021 showed reduced incidence, mortality and disability-adjusted life years overall, although there were gender and age disparities. Targeted COPD monitoring, assessment and management strategies remain important to reduce COPD burden in these countries.

In a UK study of over 134,000 women of reproductive age with asthma, the progestogen-only pill (POP) increased asthma attacks in certain asthma phenotypes.

Overall, there was no association between asthma attacks and combined oral contraceptive or POP use. However, POPs were linked to increased asthma attacks in women under 35, those with eosinophilic asthma and women with lower corticosteroid use, suggesting personalized approaches to contraception choices should be considered.

Asthma, COPD and interstitial lung disease (ILD) affect over 10 million people in the United Kingdom, often with poor respiratory outcomes.

This unique study using harmonized healthcare records from all 4 UK nations over 20 years reported an increased incidence of ILD in England, Wales, Scotland and Northern Ireland, but an overall decrease in asthma. COPD incidence, however, only decreased in England and Wales.

Asthma management was improved and emergency department visits reduced in a respiratory therapist–led community programme in California, United States.

An interdisciplinary approach incorporating home visits and educational modules, integrating clinical care with environmental and social factors, addressed some of the challenges in underserved communities and the management of chronic respiratory conditions.

CC-MED-2-03/2026

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